21C Museum Hotel Louisville

700 West Main Street, Downtown Louisville, Louisville, United States - Cultural attractions nearby
4.5/5
· 1899 reviews

Providing a central setting a few moments from Kentucky Art and Craft Gallery, the 5-star 21C Museum Hotel Louisville features a banquet hall perfect for various meetings and gatherings. Boasting bike riding and yoga, along with a 24-hour bar, this Louisville hotel is located approximately a 5-minute stroll from Kentucky Science Center.

Location

The hotel is centrally located in the business Downtown Louisville district, a stone's throw from Evan Williams Bourbon Experience Distillery. Falls of the Ohio State Park is also located 2.5 miles from the boutique-style 21C Museum Hotel. Guests might as well visit Aegon Plaza, which is only an 8-minute walk away. Entertainment options in the area feature the micro - Angel's Envy Distillery about 1 mile from the property. The 21C Museum Hotel Louisville is also situated only steps away from Main / 7th bus stop.

Rooms

The 96 allergy-friendly rooms are equipped with a flat-screen TV with satellite channels, along with a mini bar fridge and tea/coffee making equipment for guests' comfort. The rooms have elegant furniture featuring a writing desk. You can enjoy views of the urban.

Food & Drinks

The on-site restaurant, Proof On Main, serves American cuisine for dinner.

Leisure & Activities

21C Museum Hotel Louisville indulges guests with a spa salon, as well as a gym area and a fitness studio. Also, at the Louisville hotel, guests can take advantage of a golf course provided onsite. A Turkish steam bath and a sauna, along with spa service, are provided to ensure a perfect stay. Business travelers will benefit from banquet facilities and a photocopier available at a business center on site.

Why choose 21C Museum Hotel Louisville

Select room
  • Unique duct tape art exhibit

  • Luxury spa and wellness center

  • Renowned bourbon bar experience

  • Stunning downtown location access

Main amenities

  • Wi-Fi

  • Parking

  • 24-hour services

  • Fitness/Gym

  • Spa and relaxation

  • On-site Dining

  • Meeting facilities

  • Child-friendly

  • Wheelchair access

  • Air conditioning

  • Pets

General
  • Wi-Fi
  • Parking
  • 24-hour services
  • Fitness/Gym
  • Spa and relaxation
  • On-site Dining
  • Meeting facilities
  • Child-friendly
  • Wheelchair access
  • Air conditioning
  • Pets
1/35

Internet

  • Wi-Fi

Parking options

  • Parking
  • Valet parking

Activities

  • Fitness centre
  • Yoga class

Property services

  • Safe deposit box
  • 24-hour reception
  • Security
  • Luggage storage
  • Locker room
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining options

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

In the kitchen

  • Cookware/ Kitchen utensils

Business facilities

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

For kids

  • Cots

Recreation

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

For disabled guests

  • Rooms/ Facilities for disabled
  • Wheelchair access

In the rooms

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

In the bathroom

  • Free toiletries

Devices

  • Flat-screen TV

Design

  • Carpeted floor

General facilities

  • No smoking on site
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Pets

  • Pets allowed

Important information

Check-in:
from 16:00 until 23:59
Check-out:
until 11:00
  • Children and extra beds
  • Maximum capacity of extra beds in a room is 1.

Enter dates to see availability

From USD 167 per night
Check-in 3 Jun 2026
Check-out 4 Jun 2026
Guests 2 guests

Adults:

2

Children:

0
All rates verified
How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.

Rooms

Photos of 21C Museum Hotel Louisville

Location of 21C Museum Hotel Louisville

700 West Main Street, Downtown Louisville, Louisville, United States

 -  Cultural attractions nearby
Attractions
Great restaurants
Transportation

Places nearby

    Guest reviews of 21C Museum Hotel Louisville

    8.8 Fabulous
    187 reviews

    Write a review

    When did you travel?

    Your rating point

    Very bad
    Excellent

    Your details

    Where are you from?
    Thank you! Thank you for taking the time to share your experience. Your review will be published shortly.

    Review has not been sent.

    Please try again.

    Popular hotels in Louisville

    Find your perfect hotel stay today

    Popular hotels all over the world

    Find your perfect hotel stay today

    Currency
    • USD U.S. dollar
    • EUR Euro
    • GBP Pound sterling
    • AUD Australian dollar
    • CAD Canadian dollar
    • BRL Brazilian real
    • CNY Chinese yuan
    • CZK Czech koruna
    • DKK Danish krone
    • HKD Hong Kong dollar
    • ILS Israeli new sheqel
    • JPY Japanese yen
    • MYR Malaysian ringgit
    • NZD New Zealand dollar
    • NOK Norwegian krone
    • PLN Polish zloty
    • RON Romanian leu
    • RUB Russian ruble
    • SAR Saudi riyal
    • SGD Singapore dollar
    • ZAR South African rand
    • KRW South Korean won
    • SEK Swedish krona
    • CHF Swiss franc
    • TRY Turkish lira
    • UAH Ukrainian hryvnia
    • THB Thai baht
    • ARS Argentina, Peso
    Select language
    100% Verified Reviews
    Enter dates to see availability
    From USD 167 per night
    Check-in 3 Jun 2026
    Check-out 4 Jun 2026
    Guests 2 guests

    Adults:

    2

    Children:

    0
    All rates verified
    How we verified prices Our team regularly checks prices to make sure you see the lowest available rates. We compare them with hotel prices and other providers. If discounts or promotions appear, prices on our site are updated accordingly.
    Check-in & out
    3 Jun 2026
    4 Jun 2026
    Guests
    2 guests
    We're here to help
    Hi there! Have a question? Message us—our team is happy to assist.
    Your details:
    Subject:
    Message:
    Thank you for your message. We’ll get back to you shortly!
    Your message was not delivered
    Important information
    21C Museum Hotel Louisville
    Check-in:
    from 16:00 until 23:59
    Check-out:
    until 11:00
    • Children and extra beds
    • Maximum capacity of extra beds in a room is 1.